Christine's Care is a slice-of-life yuri visual novel set in early 2000s Canada. After a painful breakup with her boyfriend, Christine moves to a big city and takes on a new role as a nurse. She is assigned to care for Hannah, a woman her own age who is paralyzed from the waist down.

Christine is immediately struck by Hannah’s complexity—intelligent, beautiful, yet deeply bitter about her condition. As the story unfolds, the two women grow closer, forging a connection that might transform both of their lives. Will Christine be the one to help Hannah find new hope, or will Hannah end up changing Christine in ways she never expected?

Meanwhile, Christine encounters an unusual couple: Marlon, a muscular Latina with a commanding presence, and Liz, a delicate, half-Asian woman in a submissive role. Their dominant/submissive relationship is unlike anything Christine has experienced, but she quickly becomes fascinated by their dynamic. One day, Marlon invites her to take control and dominate Liz, an offer that Christine unexpectedly enjoys.

As Liz starts to show more interest in Christine, even hinting at wanting her over Marlon, the situation becomes dangerous. Marlon’s fiery temper is not something to take lightly. Christine now faces a choice—should she risk challenging Marlon for Liz, who she is growing attached to, or walk away from the couple’s strange and seductive world before things spiral out of control?